Hesperian Health Guides

What Causes Infertility?

In this chapter:

Problems with sperm, the testicles, or the penis can all lead to infertility. These problems can have a variety of causes.

  1. Few sperm are produced, or the sperm produced cannot fertilize an egg, possibly because of:
  2. The testicles are damaged or work differently, possibly because of:
    • illnesses like tuberculosis, mumps, or untreated STIs.
    • physical injuries.
    • a condition called varicocele that reduces blood flow to a testicle.
    • changes in hormones, which affect sperm production.
  3. The penis cannot deliver sperm to the vagina, possibly because of:
    • conditions that make ejaculation difficult or impossible, such as diabetes or spinal cord injury, or a penis that doesn’t get hard during sex.
    • an STI that damaged the tubes that carry the semen and sperm.


Problems with the egg, the womb, or the tubes can all lead to infertility. These problems can have a variety of causes.

Infertility caused by infection can be prevented. See Pelvic Inflammatory Disease and How to Prevent STIs.

blocked tube
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fibroid
  1. An egg is not produced, or an egg produced cannot develop into a fetus after fertilization, possibly because of:
  2. The womb is damaged or works differently, possibly because of:
    • growths in the womb (like fibroids) that prevent pregnancy.
    • scarring from an untreated STI, an infection after birth, or an unsafe abortion, which blocks sperm from reaching the egg or prevents a fertilized egg from attaching to the womb.
    • differences in womb shape.
    • changes in hormones that affect the womb’s lining.
  3. The tubes stop sperm from reaching an egg, possibly because of:
    • illnesses like tuberculosis or untreated STIs that damage the tubes and block the sperm.




This page was updated:22 Jan 2024