Hesperian Health Guides

Medicine Combinations to Treat Pelvic Infection

If the signs are for Pelvic Inflammatory Disease (PID) and are severe or the woman is pregnant, she will need medicines given in the vein (IV).

This infection is usually caused by a mix of germs, so at least 2 and sometimes 3 kinds of medicines are needed to cure it. Choose 1 medicine from the first two sections below. Also give metronidazole. For each section, the best choices are listed first and in order of next best after that. For example, the best combination is ceftriaxone and doxycycline. After 48 hours, if the medicines are not helping or signs are severe, get medical help.

Also treat the person’s partner using the medicines for gonorrhea and chlamydia.





Medicine for infections from gonorrhea.
Use one.
How much to give How to use
ceftriaxone 250 mg inject into muscle, 1 time only
or spectinomycin 2 grams (2000 mg) inject into muscle, 1 time only
AND
Medicine for infections from chlamydia.
Use one.
How much to give How to use
doxycycline
(do not use doxycycline if you are pregnant and avoid using it if you are breastfeeding)
100 mg by mouth, 2 times a day for 14 days
or azithromycin
(take azithromycin with food, safe during pregnancy)
1 gram (1000 mg) by mouth as a single dose, and a second dose 1 week later
or erythromycin
(safe during pregnancy)
500 mg by mouth, 4 times a day for 14 days
or amoxicillin
(amoxicillin can be used if you are pregnant and azithromycin and erythromycin are not available)
500 mg by mouth, 3 times a day for 14 days
AND
Medicine for other infections (use if it is available). How much to give How to use
metronidazole 400 to 500 mg by mouth, 3 times a day for 14 days
IMPORTANT! Do not drink alcohol while you are taking metronidazole.




This page was updated:07 Jun 2021