Hesperian Health Guides

Medicine Combinations to Treat Pelvic Infection

Sexually Transmitted Infections: Medicines

If the signs are for Pelvic Inflammatory Disease (PID) and the person is very ill with a high fever or vomiting, or pregnant, go to a health center or hospital immediately. You will need medicines given in the vein (IV). If the signs are beginning and not yet severe, the treatment may be an injection and medicines by mouth. This infection is usually caused by a mix of germs, so more than one medicine is needed.

Choose 1 medicine from the first two sections below. Also give metronidazole. For each section, the best choices are listed first and in order of next best after that. For example, the best combination is ceftriaxone and doxycycline. After 2 days, if the medicines do not seem to be working, or signs are severe, get medical help. Also treat the person’s sexual partner or partners using the medicines for gonorrhea and chlamydia.





Medicine for infections from gonorrhea.
Use one.
How much to give How to use
ceftriaxone 250 mg
(In some countries, 500 mg may be recommended instead)
inject into muscle, 1 time only
or cefixime 400 mg by mouth, 1 time only
AND
Medicine for infections from chlamydia.
Use one.
How much to give
How to use
doxycycline
(do not use doxycycline if you are pregnant and avoid using it if you are breastfeeding)
100 mg by mouth, 2 times a day for 14 days
or azithromycin
(take azithromycin with food, safe during pregnancy)
1 gram (1000 mg) by mouth, 1 time only
or erythromycin
(safe during pregnancy)
500 mg by mouth, 4 times a day for 14 days
or amoxicillin
(amoxicillin can be used if you are pregnant and azithromycin and erythromycin are not available)
500 mg by mouth, 3 times a day for 14 days
AND
Medicine for other infections (use if it is available). How much to give How to use
metronidazole 400 to 500 mg by mouth, 2 times a day for 14 days
IMPORTANT! Do not drink alcohol while you are taking metronidazole.



This page was updated:05 Jan 2024