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Medicine Combinations to Treat Both Syphilis and Chancroid

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HealthWiki > New Where There Is No Doctor > Sexually Transmitted Infections > Medicine Combinations to Treat Both Syphilis and Chancroid


It is not always possible to tell the difference between chancroid and syphilis. If you are not sure whether the person has one or the other or both, it is best to treat both at the same time. Choose 1 medicine from each box. For each section, the best choices are listed first and in order of next best after that. For example, the best combination is benzathine penicillin and azithromycin. If using erythromycin to treat syphilis, don’t use azithromycin or erythromycin for chancroid.



Medicine to treat syphilis. Use one. How much to give How to use
benzathine penicillin (can be used if pregnant) 2.4 million Units inject into muscle, one time only
or doxycycline
(do not use doxycycline if you are pregnant and avoid use if you are breastfeeding)
100 mg by mouth, 2 times a day for 14 days
or erythromycin
(Only use this if you are pregnant or breastfeeding and allergic to penicillin. It will treat syphilis in the mother, but after the birth the baby will need additional treatment)
500 mg by mouth, 4 times a day for 15 days
AND
Medicine to treat chancroid. Use one. How much to give How to use
azithromycin 1 gram (1000 mg) by mouth, one time only
or ceftriaxone 250 mg inject into muscle, one time only
or ciprofloxacin
(do not use if pregnant or breastfeeding or under age 16)
500 mg
by mouth, 2 times a day for 3 days
or erythromycin 500 mg by mouth, 4 times a day for 7 days



This page was updated:12 Jun 2019