Hesperian Health Guides
Medicine Combinations to Treat Gonorrhea and Chlamydia
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Gonorrhea and chlamydia are 2 STIs that often occur at the same time. Treat with 2 different medicines. Choose 1 medicine from each section below. For each section, the best choices are listed first and in order of next best after that. For example, the best combination is ceftriaxone and azithromycin.
Also treat the person’s partner with the same medicines.
|Medicine||How much to give||How to use|
|ceftriaxone||250 mg||inject into muscle, 1 time only|
|or cefixime||400 mg||by mouth, 1 time only|
|or spectinomycin||2 grams (2000 mg)||inject into muscle, 1 time only|
|azithromycin||1 gram (1000 mg)||inject into muscle, 1 time only|
by mouth, 1 time only
(do not use doxycycline if you are pregnant and avoid using it if you are breastfeeding)
|100 mg||by mouth, 2 times a day for 7 days|
|or erythromycin||500 mg||by mouth, 4 times a day for 7 days|
(do not use tetracycline if you are pregnant or breastfeeding)
|500 mg||by mouth, 4 times a day for 7 days|
(amoxicillin can be used if you are pregnant and azithromycin and erythromycin are not available)
|500 mg||by mouth, 3 times a day for 7 days|