Hesperian Health Guides

Medicine Combinations to Treat Gonorrhea and Chlamydia

Gonorrhea and chlamydia often occur together, so they are both treated at the same time even if you don't know which one it is. To do this, use 2 medicines, one from each section below. For each section, the best choices are listed first and in order of next best after that. For example, the best combination is ceftriaxone and azithromycin.

Also treat the person’s partner with the same medicines.









Medicine How much to give How to use
ceftriaxone
250 mg inject into muscle, 1 time only
or cefixime 400 mg by mouth, 1 time only
or
spectinomycin
2 grams (2000 mg) inject into muscle, 1 time only
AND
azithromycin 1 gram (1000 mg) inject into muscle, 1 time only
by mouth, 1 time only
or doxycycline
(do not use doxycycline if you are pregnant and avoid using it if you are breastfeeding)
100 mg by mouth, 2 times a day for 7 days
or erythromycin 500 mg by mouth, 4 times a day for 7 days
or tetracycline
(do not use tetracycline if you are pregnant or breastfeeding)
500 mg
by mouth, 4 times a day for 7 days
or amoxicillin
(amoxicillin can be used if you are pregnant and azithromycin and erythromycin are not available)
500 mg by mouth, 3 times a day for 7 days



This page was updated:07 Jun 2021