Hesperian Health Guides
Knowing how your child is doing on ART
HealthWiki > Helping Children Live with HIV > Chapter 11: ART: Medicines for HIV > Knowing how your child is doing on ART
Treatment programs may also use medical tests, usually blood tests, to measure how the child is doing on ART. The CD4 test shows how strong the childâs immune system is by measuring the amount of CD4 cells in her blood. The viral load test measures how much HIV is in the childâs blood. When the amount of virus is low, ART is working well. So you want the CD4 amount to be high or getting higher, and want the viral load to be low or getting lower.
Your childâs ART medicine may change Sometimes children have a problem with one drug in their ART combination. If this happens, that drug might be changed to another one, especially if your child has a harmful or uncomfortable side effect that does not go away.
As babies and young children grow, their ART doses change because they are based on the childâs weight. A childâs ART may also change at a certain age because he can take tablets rather than liquid medicine, or the new dose of his ART combination is available in a single pill.
ART medicines also need to be changed if your childâs ART stops working well.
What happens if ART stops working
ART can work for a very long time if taken faithfully and in the right doses. Many children with HIV are growing up healthy and strong because of ART. But sometimes ART stops working as well as it did. The cause of this is usually problems with taking the medicine every day and at the right time.
Missing just a few ART doses in a month allows HIV to change and adapt. When this happens, those ART medicines do not work as well and HIV can multiply again. This is called drug resistance. Drug resistance causes children to become sickly or develop illnesses that are difficult to treat even though they are taking ART. The childâs CD4 or viral load tests will show that drug resistance has developed. Health workers will then try other ART medicines, if they are available.
The first medicines your child takes are sometimes called âfirst-line medicines,â the first line of defense against HIV. If these medicines stop working, costlier medicines are needed, sometimes called âsecond-line medicines.â If the new medicines work well, the child will regain her health. It is even more important to give these medicines faithfully every day, because if this second-line ART stops working, there may be no third-line medicines.
ART doses and drug resistance
Drug resistance can also happen when the childâs ART doses are no longer enough for his size. As children grow â which is all the time! â their weight changes and they need more ART. If a child sees a health worker regularly, their dose of ART can be changed when necessary. This will make sure it continues to work and keep them healthy.